Name: Creamy Spinach and Artichoke Chicken Casserole Bliss
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Ingredients: 4 cups Cooked Chicken (shredded or diced); 14 ounces Artichoke Hearts (drained and chopped); 10 ounces Frozen Chopped Spinach (thawed and drained); 1 cup Mayonnaise (or Greek yogurt); 1 cup Sour Cream (or Greek yogurt); 2 cups Mozzarella Cheese (shredded); 1/2 cup Parmesan Cheese (grated); 1 teaspoon Garlic Powder; 1 teaspoon Onion Powder; 1/2 teaspoon Black Pepper; 1 teaspoon Salt; 2 tablespoons Olive Oil (for greasing); 1 cup Breadcrumbs (Panko preferred); 2 tablespoons Butter (melted); 1 cup Breadcrumbs (Panko preferred); 2 tablespoons Butter (melted)

Jump to Recipe Print Recipe

As I opened my fridge searching for inspiration, a half-eaten jar of artichoke hearts caught my eye. That moment sparked the creation of my Spinach and Artichoke Chicken Casserole, a dish that elegantly balances comfort food and convenience. With tender chicken shimmering beneath layers of creamy spinach and tangy artichokes, this cheesy bake is the answer to your busy weeknight meals. In under an hour, you can create a heartwarming feast that will have everyone requesting seconds. Not only is it easy to whip up, but it also embraces those rich, nostalgic flavors we all crave. Whether you’re gathering friends for a cozy dinner or aiming to impress with a dish at your next potluck, this casserole has you covered. Curious how a simple combination can become a family favorite? Let’s dive into the recipe!

Why is this casserole a must-try?

Comforting, Hearty Dish: This Spinach and Artichoke Chicken Casserole is the ultimate comfort food, combining rich flavors with nutritious ingredients that satisfy cravings.

Quick Preparation: Perfect for busy weeknights, this dish comes together in under an hour, making it a hassle-free dinner option for everyone.

Crowd-Pleasing Flavor: With its creamy, cheesy goodness, this casserole will have family and friends asking for seconds, whether served at a cozy dinner or festive potluck.

Versatile Ingredients: Feel free to swap the cooked chicken for chickpeas for a vegetarian twist, or add other veggies for a personalized touch!

Easy Leftover Storage: Leftovers last for several days, allowing you to enjoy this delicious dish even on busy days ahead.

Serve it alongside a fresh salad for a perfectly balanced meal and experience comfort food like never before! If you love hearty home cooking, check out my Cheddar Spinach Chicken for another delightful option!

Spinach and Artichoke Chicken Casserole Ingredients

For the Casserole
• Cooked Chicken – Opt for shredded or diced; leftover rotisserie chicken adds extra flavor.
• Artichoke Hearts – These bring an earthy flavor; you can substitute with fresh if you prefer a more vibrant taste.
• Frozen Chopped Spinach – This ingredient adds moisture and nutrients; feel free to use fresh spinach that has been sautéed and drained.
• Mayonnaise – Offers richness to the sauce; try Greek yogurt for a lighter alternative.
• Sour Cream – Adds tanginess while lightening the dish; Greek yogurt works here as well.
• Mozzarella Cheese – Provides that gooey, melty texture; switch to cheddar for a bolder flavor.
• Parmesan Cheese – Delivers a savory kick; Pecorino Romano makes a fantastic substitute.
• Garlic Powder – Infuses the dish with aromatic warmth; fresh garlic can be used but take care not to burn it.
• Onion Powder – Adds depth to the flavor; you can use fresh sautéed onions for a fresher bite.
• Black Pepper – Adds gentle heat and enhances overall flavors; white pepper can be used for a milder effect.
• Salt – Elevates all the flavors harmoniously.
• Olive Oil – Essential for greasing the baking dish; also adds a subtle flavor profile.
• Breadcrumbs – Creates a crunchy topping; Panko adds a lighter texture, which can be seasoned if desired.
• Butter – Helps the breadcrumbs crisp up beautifully while contributing richness.

For the Topping
• Breadcrumbs – Use Panko for a lighter, airier texture; season them for added flavor.
• Butter – Aids in achieving that perfect golden-brown crust over your casserole.

With these Spinach and Artichoke Chicken Casserole ingredients, you’re on your way to creating a dish that’s not only comforting but also bursting with flavor. Happy cooking!

Step‑by‑Step Instructions for Spinach and Artichoke Chicken Casserole

Step 1: Preheat the Oven
Begin by preheating your oven to 375°F (190°C). This ensures your Spinach and Artichoke Chicken Casserole cooks evenly, developing a golden crust on top. While the oven is warming up, gather all your ingredients and the necessary baking dish, making your cooking process smoother and more enjoyable.

Step 2: Prepare the Filling
In a large mixing bowl, combine your cooked chicken, artichoke hearts, and thawed spinach. Use a fork to break up the spinach and mix thoroughly for an evenly distributed filling. The mixture should look vibrant and well-blended, ready to be transformed into a comforting casserole.

Step 3: Add Creamy Ingredients
Next, stir in the mayonnaise, sour cream, mozzarella cheese, Parmesan cheese, garlic powder, onion powder, black pepper, and salt. Mix everything together until it’s creamy and smooth, making sure every morsel of chicken and vegetable is coated in that delightful cheesy goodness. This will create a rich and flavor-packed filling for your casserole.

Step 4: Grease the Baking Dish
Take a 9×13 inch baking dish and drizzle a bit of olive oil in it, using a paper towel or your fingers to spread it evenly across the bottom and sides. This will prevent your Spinach and Artichoke Chicken Casserole from sticking, allowing for easy serving later. The shiny coated surface is a welcoming stage for your delicious creation.

Step 5: Assemble the Casserole
Spread the chicken mixture evenly in the greased baking dish. Smooth out the mixture with a spatula to ensure even cooking throughout. As the casserole bakes, it will puff up slightly and the flavors will meld, creating a delightful layer of comfort food that is simply irresistible.

Step 6: Prepare the Topping
In a small bowl, melt some butter and then mix it with the breadcrumbs until they are completely coated. This will make your topping crispier and more flavorful as it bakes on top of the casserole, adding a satisfying texture contrast. Give the mixture a quick stir to ensure that each breadcrumb is coated.

Step 7: Add Breadcrumbs and Cheese
Sprinkle the breadcrumb mixture over the casserole, ensuring an even distribution across the top. Follow this by adding any remaining mozzarella and Parmesan cheese. These layers will create a beautiful, cheesy crust on your Spinach and Artichoke Chicken Casserole, promising a delightful look when it comes out of the oven.

Step 8: Bake the Casserole
Cover the baking dish with foil and place it in the preheated oven. Bake for 20 minutes, allowing the casserole to heat through without browning too quickly. After 20 minutes, remove the foil and continue baking for an additional 10-15 minutes or until the topping is golden and bubbly. You’ll know it’s done when it looks irresistibly inviting.

Step 9: Cool and Serve
Once baked, take the casserole out of the oven and let it cool for a few minutes before serving. This cooling period helps the layers to set, making it easier to slice and serve. The every-bite comfort of this Spinach and Artichoke Chicken Casserole will have everyone coming back for more!

What to Serve with Spinach and Artichoke Chicken Casserole

A delicious meal is just an accompaniment away, turning your comforting casserole into a true feast.

Simple Green Salad: A fresh, crisp salad dressed in lemon vinaigrette provides a zesty contrast to the creamy casserole, balancing flavors perfectly. The crunch of cool greens sets a vibrant tone for your meal.
Toasted Garlic Bread: This savory side is irresistible, offering a crunchy texture and robust flavor. It’s perfect for scooping up any cheesy remnants left on your plate, making each bite an indulgent delight.
Roasted Vegetables: Colorful roasted veggies like carrots, bell peppers, or zucchini add a delightful crunch and extra nutrients. Their natural sweetness complements the creamy richness of the casserole beautifully.
Steamed Broccoli: Bright green broccoli maintains a tender bite and provides a fresh, earthy flavor that pairs wonderfully with the rich casserole. Drizzle with a squeeze of lemon to enhance its vibrancy.
Creamy Mashed Potatoes: Buttery, smooth mashed potatoes are a classic comfort side that harmonizes well with the casserole’s cheesy goodness. Each forkful is a warm embrace of flavors that will leave you satisfied.
White Wine: A chilled glass of Sauvignon Blanc or Pinot Grigio enhances the dining experience with its crisp acidity, perfectly cutting through the richness of the casserole while complimenting its savory profile.
Chocolate Lava Cake: For dessert, serve a warm chocolate lava cake that offers a delightful contrast to the savory meal. Its richness and gooey center make for an unforgettable sweet finish.

Feel free to mix and match these suggestions to create a well-rounded, enjoyable meal that showcases the comforting qualities of your Spinach and Artichoke Chicken Casserole!

How to Store and Freeze Spinach and Artichoke Chicken Casserole

Fridge: Store leftovers in an airtight container for up to 3-4 days. Reheat portions at 350°F (175°C) covered with foil to keep them moist.

Freezer: You can freeze the assembled casserole before baking for up to 2 months. Thaw overnight in the fridge, then bake as directed for a fresh meal.

Reheating: To ensure even heating, reheat in the oven at 350°F (175°C) covered with foil for about 20 minutes, then uncover for an additional 10 minutes to crisp the top.

Portion Control: Consider freezing individual portions for quicker meals on busy nights. This makes it easy to enjoy your Spinach and Artichoke Chicken Casserole any time!

Spinach and Artichoke Chicken Casserole Variations

Feel free to embrace creativity and tailor this casserole to your liking with some delightful twists and substitutions!

Vegetarian Option: Replace the chicken with chickpeas for a deliciously hearty vegetarian dish that maintains that satisfying feel.
Fresh Spinach: Use fresh sautéed spinach instead of frozen. Sautéing brings out its vibrant flavor and reduces excess moisture for a creamier texture.
Flavor Boost: Add a tablespoon of hot sauce or a sprinkle of red pepper flakes to give your casserole a bit of heat that pairs beautifully with the creamy base.
Mixed Veggies: Incorporate other vegetables such as bell peppers, zucchini, or mushrooms for added nutrition and diverse flavors. These vegetables can create a heartier bite.
Cheese Alternatives: Swap mozzarella for pepper jack cheese for a creamy, spicy kick that will heat things up even more!
Herbs: Enhance the flavor profile with fresh herbs like parsley or basil sprinkled before serving. A fresh touch can elevate the dish beautifully.
Breadcrumbs Variations: Try using seasoned Panko breadcrumbs or even crushed Ritz crackers for an irresistible crunch that adds a buttery flavor to the topping.
Make it Low-Carb: Substitute the breadcrumbs with crushed pork rinds or omit them entirely to create a lighter, low-carb version of the casserole without losing richness in flavor.

If you’re looking for more delicious recipes to expand your home cooking repertoire, don’t miss trying out my Crack Chicken Casserole or our delectable Ground Beef and Spinach Skillet with Feta. Happy cooking!

Make Ahead Options

These Spinach and Artichoke Chicken Casseroles are perfect for meal prep enthusiasts seeking time-saving strategies! You can assemble the casserole up to 24 hours in advance by following the recipe up to the baking step (just cover with foil and refrigerate). To maintain quality, ensure all ingredients are well-mixed and seal tightly to prevent any drying out. When you’re ready to enjoy your meal, simply preheat the oven and bake directly from the fridge, adding an extra 5-10 minutes to the baking time if it’s still chilled. This way, you can savor a comforting, homemade dinner with minimal effort on a busy night!

Expert Tips for Spinach and Artichoke Chicken Casserole

Mix Thoroughly: Ensure all ingredients are well combined for consistent flavor and texture throughout the casserole. No one likes a bite that’s too bland!
Watch the Browning: Cover the casserole for the first part of baking to avoid over-browning; uncover only in the last 10-15 minutes for that perfect golden crust.
Let it Rest: Allow the casserole to cool for a few minutes before serving. This helps set the layers and makes slicing much easier.
Customize Wisely: Swap out the chicken for chickpeas for a tasty vegetarian option. Adding more veggies, like bell peppers or mushrooms, can enhance flavor and nutrition.
Breadcrumb Alternatives: Use Panko breadcrumbs for a light, crunchy topping. Season them with herbs or spices to elevate the dish’s flavor even more.
Storage Tips: Leftovers can be refrigerated for 3-4 days or frozen for up to 2 months. Reheat covered at 350°F (175°C) for best results.

Spinach and Artichoke Chicken Casserole Recipe FAQs

What type of chicken should I use for this casserole?
Absolutely! I recommend using cooked chicken, either shredded or diced. Leftover rotisserie chicken adds an extra flavor boost, making your casserole even more delicious!

How do I store leftovers from the casserole?
Once cooled, store leftovers in an airtight container in the fridge for up to 3-4 days. When you’re ready to enjoy them again, simply reheat at 350°F (175°C) covered with foil to maintain moisture.

Can I freeze this casserole and how?
Yes, you can freeze the assembled casserole before baking! Wrap it tightly in plastic wrap and aluminum foil, then freeze for up to 2 months. To enjoy, thaw overnight in the fridge and bake as directed. For best results, reheat covered at 350°F (175°C) for about 20 minutes before uncovering to crisp the top.

How can I customize the flavors of this casserole?
Feel free to mix it up! You can substitute cooked chicken for chickpeas for a vegetarian twist. Throw in additional veggies, like mushrooms or bell peppers, for extra nutrition. If you like heat, adding red pepper flakes or diced jalapeños can spice things up!

Is this casserole suitable for people with dietary restrictions?
Great question! If there are concerns about allergies, you can substitute mayonnaise and sour cream with Greek yogurt for a lighter option. Be sure to check the labels of your ingredients to avoid any allergens, especially when serving guests or family members with food sensitivities!

What should I do if the casserole browns too quickly?
If you notice your casserole browning too fast, cover it with foil during the baking process. This helps prevent over-browning while still allowing the insides to cook thoroughly. Remove the foil during the last 10-15 minutes to achieve that golden topping everyone loves!