Name: Ham and Cheese Casserole: The Ultimate Comfort Dish
Prep time: 15 min
Cook time: 30 min
Total time: 55 min
Ingredients: 12 oz Medium Pasta Shells (Rotini or penne can be alternatives.); 4 Tbsp Butter (Use unsalted for better control over saltiness.); 1/4 cup All-Purpose Flour (Creates the roux for thickening the cheese sauce.); 1 tsp Onion Powder (Fresh onions can be sautéed for a fresh twist.); 1 tsp Garlic Powder (1 clove fresh garlic = 1/8 teaspoon powder.); 1 tsp Dried Thyme (Oregano or favorite dried herb can be swapped.); to taste Salt (Adjust to suit your personal taste.); to taste Pepper (Adjust to suit your personal taste.); 2 cups Whole Milk or Half & Half (Opt for low-fat milk for a lighter option.); 1 Tbsp Dijon Mustard (Yellow mustard can be substituted if desired.); 2 cups Sharp Cheddar Cheese (Consider mixing with other cheeses for diversity.); 1 cup Gruyere Cheese (Fontina or mozzarella can be used for a milder taste.); 2 cups Diced Cooked Ham (Leftover ham can be replaced with chicken or turkey.); 1 cup Panko Breadcrumbs (Regular breadcrumbs can be substituted if needed.); 1/2 cup Parmesan Cheese (Pecorino Romano brings an extra sharp bite.); 2 Tbsp Salted Butter (for topping) (Use unsalted butter but add salt to topping if necessary.)

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As I rummaged through the fridge, I stumbled upon a generous portion of leftover ham, just waiting to be transformed. Enter the Ham and Cheese Casserole—a delightful, creamy dish that turns those remnants into a comforting family meal. Not only is this recipe quick to prepare, but it also guarantees smiles from both kids and adults alike, making it a perfect weeknight savior. With tender pasta, savory ham, and a crispy Panko topping, every bite offers a warm hug for your taste buds. Plus, it’s customizable; feel free to toss in your favorite veggies or change up the cheese to keep things exciting! Are you ready to give this easy casserole a try and elevate those leftovers into something extraordinary?

Why is this casserole a must-try?

Family-Friendly: This Ham and Cheese Casserole is designed for all ages, ensuring even the pickiest eaters will devour every bite!

Quick to Assemble: With simple ingredients and just 30 minutes in the oven, it’s perfect for busy weeknights when time is tight.

Customizable Fun: Add your favorite vegetables or switch up the cheese blend for a unique twist; the possibilities are endless!

Comforting Delight: The creamy sauce and crispy topping create a warm, indulgent experience reminiscent of classic comfort food.

Crowd-Pleaser: Whether it’s a family dinner or a potluck, this dish is sure to impress and satisfy everyone at the table.

For other family-friendly recipes, check out my Chicken Rice Casserole or try these Greek Potatoes Feta for a delightful side!

Ham and Cheese Casserole Ingredients

For the Casserole

Medium Pasta Shells – Provides the main structure of the casserole; rotini or penne can be wonderful alternatives.
Butter – Adds richness and flavor; unsalted butter allows for more control over the saltiness of the dish.
All-Purpose Flour – Creates the roux for thickening the cheese sauce; suitable for those who don’t need gluten-free options.
Onion Powder – Enhances the savory flavor; fresh onions can be sautéed for a fresh twist.
Garlic Powder – Imparts a lovely aroma; fresh garlic works as a great substitution (1 clove = 1/8 teaspoon powder).
Dried Thyme – Adds earthy notes, but feel free to swap it with oregano or your favorite dried herb.
Salt & Pepper – Essential for balance; adjust to suit your personal taste.
Whole Milk or Half & Half – Creates a wonderfully creamy sauce; opt for low-fat milk for a lighter option.
Dijon Mustard – Introduces a tangy flavor that enhances the cheese; yellow mustard can be substituted if desired.
Sharp Cheddar Cheese – Key flavor in the cheese sauce; consider mixing with other cheeses for diversity.
Gruyere Cheese – Offers melty sophistication; you may use Fontina or mozzarella for a milder taste.
Diced Cooked Ham – The heart of this dish; leftover ham can be replaced with chicken or turkey for variety.
Panko Breadcrumbs – Provides a delightful crispy topping; regular breadcrumbs work as a substitute if needed.
Parmesan Cheese – Adds a salty finish to the breading; Pecorino Romano brings an extra sharp bite.
Salted Butter (for topping) – Enhances the breadcrumb flavor; use unsalted butter but add salt to the topping if necessary.

Cooking Tips
Make sure to gather these ingredients ahead of time, as everything comes together quickly to create this Ham and Cheese Casserole that’s sure to warm your family’s hearts!

Step‑by‑Step Instructions for Ham and Cheese Casserole

Step 1: Preheat the Oven
Begin by preheating your oven to 350°F (175°C). While it warms up, grab a 9×13-inch baking dish and lightly grease it with butter or cooking spray. This will ensure that your delicious Ham and Cheese Casserole doesn’t stick while baking, making cleanup a breeze.

Step 2: Cook the Pasta
Bring a large pot of salted water to a boil and add the medium pasta shells. Cook them for about 6-8 minutes until they’re just under al dente, as they will continue to cook in the oven. Once cooked, drain the pasta, reserving a cup of the cooking water, and set it aside to cool slightly.

Step 3: Make the Roux
In a medium saucepan, melt 4 tablespoons of butter over medium heat. Once melted, whisk in ¼ cup of all-purpose flour, along with 1 teaspoon each of onion powder and garlic powder. Stir continuously for about 2 minutes to create a smooth roux that has a light golden color, eliminating the raw flour taste.

Step 4: Prepare the Cheese Sauce
Slowly pour in 2 cups of whole milk or half-and-half while whisking to incorporate it smoothly. Continue to cook over medium heat, stirring frequently until the mixture thickens, about 4-5 minutes. Then, mix in 1 tablespoon of Dijon mustard and gradually add 2 cups of sharp cheddar cheese and 1 cup of Gruyere cheese, stirring until melted and creamy.

Step 5: Combine Ingredients
Remove the saucepan from heat and gently fold in the cooked pasta and 2 cups of diced ham, ensuring everything is evenly coated in the rich cheese sauce. If the mixture seems too thick, add a little reserved pasta water to loosen it up.

Step 6: Assemble the Casserole
Transfer the cheesy pasta and ham mixture into the prepared baking dish, spreading it evenly. Top the casserole with an additional 1 cup of mixed cheese and 1 cup of Panko breadcrumbs for that delightful crispy layer. This will create a beautiful golden crust when baked.

Step 7: Bake to Perfection
Place the baking dish in the preheated oven and bake for 20-25 minutes, until the casserole is bubbly and the top is golden brown. Keep an eye on it towards the end to avoid over-browning. The sight of the melty, crispy topping will be enticing!

Step 8: Rest Before Serving
Once baked to perfection, remove the Ham and Cheese Casserole from the oven and let it rest for about 10 minutes. This allows the sauce to settle, making it easier to serve. Enjoy this crowd-pleaser as a delightful family meal that everyone will love!

Make Ahead Options

These Ham and Cheese Casserole make-ahead options are perfect for busy weeknights when time is tight! You can prepare the casserole mixture (pasta, cheese sauce, and ham) up to 24 hours in advance. Just follow the recipe through Step 5, then cover and refrigerate the mixture. To maintain quality, avoid adding the breadcrumb topping until you’re ready to bake, as this ensures a crispy finish. When it’s time to serve, preheat your oven to 350°F (175°C) and transfer the mixture to your baking dish, topping with breadcrumbs and cheese before baking for 20-25 minutes until bubbly and golden. Enjoy a comforting meal with minimal effort!

Expert Tips for Ham and Cheese Casserole

Quality Ingredients: Use high-quality cheese for a richer flavor in your Ham and Cheese Casserole. Opt for sharp cheddar and Gruyere to elevate the dish.
Veggie Boost: Add your favorite vegetables like broccoli or peas for a nutritious twist. This not only enhances flavor but also adds color and texture.
Pasta Cooking Time: Cook the pasta just under al dente; it will continue to cook in the oven. This prevents mushiness and ensures perfect texture.
Resting Period: Allow the casserole to rest for 10 minutes after baking. This helps the sauce settle, making it easier to serve without falling apart.
Storage Tips: If you have leftovers, let them cool completely before storing them in an airtight container. This keeps your Ham and Cheese Casserole fresh for up to four days.

How to Store and Freeze Ham and Cheese Casserole

Fridge: Store leftover Ham and Cheese Casserole in an airtight container for up to 3-4 days. Ensure it cools completely before refrigeration to maintain freshness.

Freezer: For longer storage, freeze the casserole in a freezer-safe container or wrap tightly in aluminum foil for up to 3 months. Thaw in the refrigerator before reheating.

Reheating: Reheat covered with foil in a preheated oven at 325°F (165°C) for about 20-25 minutes or until heated through. Adding a splash of milk can help revive the creamy texture.

Ham and Cheese Casserole Variations

Feel free to let your culinary creativity shine as you tailor this Ham and Cheese Casserole to suit your family’s tastes!

Dairy-Free: Use plant-based milk and vegan cheeses. You won’t sacrifice creaminess while keeping it dairy-free!
Spicy Kick: Incorporate diced jalapeños or use pepper jack cheese to add a fun, fiery flavor to your casserole. Just the right amount of heat will keep everyone on their toes!
Vegetable Delight: Toss in spinach or roasted bell peppers for added nutrition and color. Not only do they enhance taste, but they also make your casserole more vibrant!
Smoky Flavor: Add smoked paprika or stir in some bacon bits for a deliciously smoky twist. This will elevate the dish in ways that bring warmth and depth.
Pasta Alternatives: Swap medium pasta shells for spiralized zucchini or cauliflower rice for a low-carb version. This makes the casserole lighter while still packed with flavor!
Cheesy Bliss: Mix in some cream cheese or ricotta along with your other cheeses for an extra creamy texture. You’ll create a rich and indulgent dish that’s hard to resist.
Protein-Packed: Substitute ham with shredded rotisserie chicken or turkey for a different protein punch. This keeps it versatile and delicious!
Herb Infusion: Fresh herbs like basil or parsley can be added to brighten the flavors. A touch of freshness will elevate the overall profile of your casserole.

As you’re experimenting, be sure to check out our Antipasto Cream Cheese Log or Cheese Steak Homemade for more inventive ideas to inspire your kitchen adventures! Enjoy delicious discoveries on this culinary journey!

What to Serve with Leftover Ham and Cheese Casserole

Savor a delightful meal that will keep your family’s taste buds dancing with these delicious pairings.

Garlic Bread: The buttery, garlicky flavor of garlic bread offers a perfect contrast, making every bite enriching.
Steamed Broccoli: A pop of green that adds crunch and nutrition, balancing the creamy casserole with a fresh element. This pairing enhances the meal with color and texture.
Simple Green Salad: A light, colorful salad topped with a tangy vinaigrette adds freshness to counter the richness of the casserole.
Roasted Carrots: Sweet, caramelized roasted carrots provide earthy flavors that harmonize beautifully with the ham and cheese.
Creamy Coleslaw: The crunchy, tangy coleslaw adds a refreshing crunch and brightens up the casserole with its zesty flavors.
Mashed Potatoes: Silky, buttery mashed potatoes create a cozy combination, giving a hearty touch that complements the casserole effectively.
Fruit Salad: A refreshing fruit medley brings a sweet touch, cleansing the palate and adding a hint of brightness to the meal.
Crisp Riesling: A chilled glass of Riesling offers a sweet and fruity contrast that pairs wonderfully with the savory elements of the casserole.
Chocolate Chip Cookies: End your meal with warm chocolate chip cookies for a comforting, sweet finish that everyone will love!

Ham and Cheese Casserole Recipe FAQs

What kind of pasta works best for this casserole?
Absolutely! Medium pasta shells are perfect for this Ham and Cheese Casserole as they hold the creamy sauce nicely. However, you can also use rotini or penne if that’s what you have on hand.

How should I store leftovers?
For best results, store leftover casserole in an airtight container in the fridge for up to 3-4 days. Make sure it’s completely cooled before placing it in the fridge to maintain freshness.

Can I freeze the Ham and Cheese Casserole?
Yes, you can freeze this casserole! Wrap it tightly in aluminum foil and place it in a freezer-safe container for up to 3 months. When ready to eat, simply thaw it in the refrigerator overnight, then reheat it in the oven at 325°F (165°C) until heated through.

What should I do if my sauce is too thick?
If your cheese sauce becomes too thick, don’t worry! Just add a splash of reserved pasta cooking water to loosen it up. Stir it in gradually until you reach your desired consistency—it should be creamy, not runny.

Are there any dietary considerations for this recipe?
Certainly! This dish is customizable to fit various dietary needs. You can substitute the ham with shredded chicken or turkey, and if you’re looking for a gluten-free option, just use gluten-free pasta and flour. Always double-check labels for any allergens, especially with the cheese and breadcrumbs.

How do I make the casserole ahead of time?
To prepare in advance, assemble the casserole but do not bake it. Cover tightly and refrigerate for up to a day ahead. When you’re ready, bake it as instructed, adding 5-10 minutes to the baking time if it starts cold from the fridge. Enjoy this convenient make-ahead dish!